Pelletier began working as a professional comic artist in the late 1980s. His first work appeared in Cosmic Steller Rebellers (hammac publications) and Wayward warrior (hammac Publications) later Zen: Intergalactic Ninja. He has worked for renowned comics publishers DC Comics and Marvel Comics as well as for the now out of business Cross Generation Entertainment. His portfolio includes stints as regular artist or guest artist on such series as Darkstars, Flash, Green Lantern, Guy Gardner, Legion of Super-Heroes, Outsiders, Superboy and the Ravers, Superman, Superman: The Man of Steel, Titans, She-Hulk, Fantastic Four, Exiles, Negation and Negation War. On top of that Pelletier has drawn special projects such as the mini-series Green Lantern/ Sentinel: Heart of Darkness or the One-shots Flash: Secret Files, Green Lantern: Secret Files and President Luthor Secret Files.
His most recent project is the Marvel Comics miniseries War of Kings and "Fall of the Hulks".
The roster of authors he has collaborated with includes writers Ron Marz, Tony Bedard, Chris Claremont and Karl Kesel.
Pelletier was one of the regular artists on Aquaman during DC's New 52.